Qualitative evaluations of courses prove difficult due to low response rates. Online courses may permit the analysis of qualitative feedback provided by health care providers (HCPs) during and after the course is completed. This study describes the use of qualitative methods for an online continuing medical education (CME) course through the analysis of HCP feedback for the purpose of quality i...

In this report, a new series of fluoroquinolone agents which was derived from levofloxacin was synthesized and evaluated against Gram-positive (Bacillus subtillis, Staphylococcus aureus, Staphylococcus epidermidis and Micrococcus luteus) and Gram-negative (Esherichio coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Serratia marcescens) organisms. The results showed that some of the synth...

A chemical library of carboxamide-substituted tetramates designed by analogy with antibacterial natural products, a method for their rapid construction, and the evaluation of their antibacterial activity is reported.

A new series of quinoline derivatives incorporated to glycosides and biologically active heterocyclic moieties were synthesized starting with 6-bromo-4-hydroxyquinaldine (6-bromo-4-hydroxy-2-methylquinoline) compound 1. Some of the synthesized compounds were evaluated for their antibacterial and antifungal activities. Most of the tested compounds exhibited potential antibacterial activity again...

Quaternary ammonium salts are frequently used as antibacterial agent that disrupts cell membrane through the binding of their ammonium cations to anionic sites in the outer layer tissue of bacteria. This article describes the synthesis of quaternary ammonium salt-type antibacterial agents with a phosphate group that strongly binds to hydroxyapatite and bromide ion as counterion. Evaluation of t...

This chapter is undertaken with a view to survey important scientific research and developmental works pertaining to antibacterial modification of textiles using nanotechnology as a new means to achieve such textiles. Inevitably, conventional antimicrobial agents and their applications to textiles are reported. This is followed by a focus on inorganic nanostructured materials that acquire good ...

We determined the prevalence of plasmid-mediated quinolone resistance mechanisms among non-Typhi Salmonella spp. isolated from humans, food animals, and retail meat in the United States in 2007. Six isolates collected from humans harbored aac(6')Ib-cr or a qnr gene. Most prevalent was qnrS1. No animal or retail meat isolates harbored a plasmid-mediated mechanism.

This study reports the synthesis and evaluation of a novel furanone-containing antibacterial resin composite. Compressive strength (CS) and S. mutans viability were used to evaluate the mechanical strength and antibacterial activity of the composites. With 5% to 30% addition of the furanone derivative, the composite showed no change in CS but a significant antibacterial activity with a 16% 68% ...

background and objectives: dorema ammoniacum d. don (apiaceae) is a monocarpic plant endemic to central iran. the gum resin of this species is a known therapeutic agent in iranian, indian and western traditional medicines. the aim of the present study was to investigate essential oil constituents and evaluation of antioxidant and antibacterial activities of the essential oils and extracts of d....

The pharmacokinetics of the quinolone enoxacin were studied after a 600-mg oral dose was given to each of six male volunteers. The levels of the compound were measured in serum, blister fluid, and urine. Absorption was variable, with peak levels (mean, 3.7 micrograms/ml) being attained between 0.75 and 3.0 h (mean, 1.9 h). The serum elimination half-life was 6.2 h, and 71.6% of the drug was rec...